INT262996

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Context Info
Confidence 0.13
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (ADIPOQ, INS) extracellular region (ADIPOQ, INS) generation of precursor metabolites and energy (ADIPOQ)
small molecule metabolic process (INS) endoplasmic reticulum (ADIPOQ) carbohydrate metabolic process (INS)
Anatomy Link Frequency
platelets 1
smooth muscle cells 1
ADIPOQ (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 95.20 Very High Very High Very High
Angina 10 28.24 Quite Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 95.20 Very High Very High Very High
Atherosclerosis 34 91.16 High High
Acute Coronary Syndrome 18 79.12 Quite High
Diabetes Mellitus 22 70.36 Quite High
Adhesions 2 68.40 Quite High
Apoptosis 4 59.04 Quite High
Atherosclerotic Plaque 32 55.68 Quite High
Pathologic Constriction 4 40.32 Quite Low
Calcification 6 33.92 Quite Low
Cv General 3 Under Development 2 28.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to its beneficial effects on insulin sensitivity and lipid metabolism [28], adiponectin exerts its vasculoprotective effects through its direct actions on endothelial cells, monocytes, macrophages and other inflammatory cells, platelets and smooth muscle cells, thus modulating initiation and progression of atherosclerosis.
adiponectin Regulation (effects) of insulin in smooth muscle cells associated with inflammation and atherosclerosis
1) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2649379 Disease Relevance 0.63 Pain Relevance 0.05
In addition to its beneficial effects on insulin sensitivity and lipid metabolism [28], adiponectin exerts its vasculoprotective effects through its direct actions on endothelial cells, monocytes, macrophages and other inflammatory cells, platelets and smooth muscle cells, thus modulating initiation and progression of atherosclerosis.
adiponectin Regulation (effects) of insulin in platelets associated with inflammation and atherosclerosis
2) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2649379 Disease Relevance 0.63 Pain Relevance 0.05

General Comments

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