INT263047

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Context Info
Confidence 0.53
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 3.61
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp9) extracellular space (Mmp9) aging (Mmp9)
extracellular region (Mmp9) proteinaceous extracellular matrix (Mmp9) extracellular matrix organization (Mmp9)
Anatomy Link Frequency
blood 2
Mmp9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 148 100.00 Very High Very High Very High
endometriosis 69 97.40 Very High Very High Very High
ischemia 24 96.20 Very High Very High Very High
anesthesia 20 70.72 Quite High
Hippocampus 5 58.40 Quite High
Inflammation 32 57.32 Quite High
Glutamate 3 53.12 Quite High
fibrosis 40 52.08 Quite High
alcohol 1 12.64 Low Low
cytokine 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 50 99.68 Very High Very High Very High
Stroke 171 98.88 Very High Very High Very High
Endometriosis 99 97.40 Very High Very High Very High
Cv General 4 Under Development 11 96.56 Very High Very High Very High
Hypoxia 39 77.68 Quite High
Middle Cerebral Artery Infarction 93 68.60 Quite High
Adhesions 7 57.88 Quite High
INFLAMMATION 34 57.32 Quite High
Body Weight 3 56.96 Quite High
Injury 34 55.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MMP-9 mRNA expression in the blood following tPA treated ischemic stroke remains poorly studied.
Transcription (expression) of MMP-9 in blood associated with stroke
1) Confidence 0.53 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2875237 Disease Relevance 0.66 Pain Relevance 0.06
to measure the activity of MMP-2 and MMP-9 by zymography.


Transcription (activity) of MMP-9 associated with metalloproteinase
2) Confidence 0.44 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2649867 Disease Relevance 0.11 Pain Relevance 0.20
We found MMP-9 mRNA to be reduced at 24 hours.
Transcription (found) of MMP-9
3) Confidence 0.39 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2875237 Disease Relevance 0.64 Pain Relevance 0.06
Further study is required to better delineate MMP-9 mRNA expression patterns in blood, including the relationship with vascular reperfusion, duration of cerebral ischemia, treatment with tPA, and correlation with expression patterns of MMP-9 in cerebral tissue.


Transcription (expression) of MMP-9 in blood associated with cv general 4 under development and ischemia
4) Confidence 0.39 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2875237 Disease Relevance 0.74 Pain Relevance 0.14
MMP9 mRNA was not expressed by the tumour and this was confirmed by negative staining with MMP9 antibody on cryosections and lack of activity in zymograms (data not shown).
Neg (not) Transcription (expressed) of MMP9 associated with cancer
5) Confidence 0.33 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2661078 Disease Relevance 0.51 Pain Relevance 0
Expression of mRNA encoding for VEGF, Flk-1 and MMP-9
Transcription (encoding) of MMP-9
6) Confidence 0.29 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2826344 Disease Relevance 0.64 Pain Relevance 0.14
The relative mRNA expression of MMP-9 was significantly increased in the 21% group compared with all of the others (Fig. 4).
Transcription (expression) of MMP-9
7) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000320 Disease Relevance 0.31 Pain Relevance 0.06

General Comments

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