INT263049

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Mmp2, Mmp9) extracellular space (Mmp2, Mmp9) peptidase activity (Mmp2, Mmp9)
extracellular region (Mmp2, Mmp9) proteinaceous extracellular matrix (Mmp2, Mmp9) extracellular matrix organization (Mmp9)
Anatomy Link Frequency
lung 2
Mmp2 (Rattus norvegicus)
Mmp9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 122 100.00 Very High Very High Very High
fibrosis 40 98.08 Very High Very High Very High
Inflammation 23 72.52 Quite High
cytokine 7 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 2 99.64 Very High Very High Very High
Pulmonary Fibrosis 28 98.48 Very High Very High Very High
Disease 2 90.00 High High
Fibrosis 23 75.88 Quite High
INFLAMMATION 22 72.52 Quite High
Injury 8 70.84 Quite High
Chronic Disease 1 62.64 Quite High
Edema 5 5.00 Very Low Very Low Very Low
Adult Respiratory Distress Syndrome 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies showed that the activity of MMP-2 and MMP-9 is upregulated in many pulmonary diseases including pulmonary fibrosis,3-7 and they are secreted by many different kinds of cells in the lungs.8-11 But, the studies dealing with human lung can provide only a snap shot at a certain time point in its long course of disease.
Positive_regulation (upregulated) of MMP-2 Binding (activity) of MMP-9 in lung associated with fibrosis, pulmonary disease, metalloproteinase, pulmonary fibrosis and disease
1) Confidence 0.35 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2649867 Disease Relevance 0.83 Pain Relevance 0.69

General Comments

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