INT263119

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDE3A) signal transduction (PDE3A) lipid metabolic process (PDE3A)
Anatomy Link Frequency
platelets 3
adipocytes 1
PDE3A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 76 5.00 Very Low Very Low Very Low
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 4 93.48 High High
INFLAMMATION 88 5.00 Very Low Very Low Very Low
Pulmonary Disease 62 5.00 Very Low Very Low Very Low
Disease 12 5.00 Very Low Very Low Very Low
Hypertension 10 5.00 Very Low Very Low Very Low
Vomiting 10 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 8 5.00 Very Low Very Low Very Low
Nicotine Addiction 6 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Natriuresis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphorylation of PDE3 is important in activating PDE3 in response to a variety of extracellular signals in cardiac, vascular and airway smooth muscle, as well as a number of other cells, including adipocytes and platelets (Degerman et al 1997).
Positive_regulation (important) of Phosphorylation (Phosphorylation) of PDE3 in platelets associated with obesity
1) Confidence 0.21 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650605 Disease Relevance 0.09 Pain Relevance 0
Phosphorylation of PDE3 is important in activating PDE3 in response to a variety of extracellular signals in cardiac, vascular and airway smooth muscle, as well as a number of other cells, including adipocytes and platelets (Degerman et al 1997).
Positive_regulation (important) of in adipocytes Phosphorylation (Phosphorylation) of PDE3 in platelets associated with obesity
2) Confidence 0.07 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650605 Disease Relevance 0.09 Pain Relevance 0

General Comments

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