INT263177

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDE3A) signal transduction (PDE3A) lipid metabolic process (PDE3A)
PDE3A (Homo sapiens)
COPD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 38 95.28 Very High Very High Very High
Inflammatory response 1 78.96 Quite High
Inflammatory mediators 4 56.64 Quite High
cytokine 1 15.04 Low Low
chemokine 1 14.16 Low Low
adenocard 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 31 100.00 Very High Very High Very High
INFLAMMATION 44 95.28 Very High Very High Very High
Disease 6 94.24 High High
Nicotine Addiction 3 80.96 Quite High
Congenital Anomalies 1 34.88 Quite Low
Weight Loss 1 33.44 Quite Low
Hypertension 5 5.00 Very Low Very Low Very Low
Vomiting 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Most interest in PDE isoforms from the perspective of COPD has centered on the PDE4 family, but PDE1, PDE3, PDE5, and PDE7 may also be of interest as therapeutic targets in COPD.
PDE3 Binding (targets) of COPD associated with pulmonary disease
1) Confidence 0.01 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650605 Disease Relevance 1.00 Pain Relevance 0.15

General Comments

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