INT263184

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Eif2b1) plasma membrane (Eif2b1) translation (Eif2b1)
cytoplasm (Eif2b1)
Eif2b1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neurotransmitter 1 86.04 High High
Inflammation 38 54.24 Quite High
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 31 76.84 Quite High
INFLAMMATION 44 54.24 Quite High
Hypertrophy 1 36.80 Quite Low
Hyperplasia 2 35.52 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Hypertension 5 5.00 Very Low Very Low Very Low
Vomiting 5 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Nicotine Addiction 3 5.00 Very Low Very Low Very Low
Natriuresis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The level of intracellular cAMP is regulated by the balance of activity between adenyl cyclase (AC), which is responsible for its formation and cyclic nucleotide phosphodiesterase which is responsible for its inactivation. cAMP exerts its effects through activation of protein kinase A (PKA), the GTP-exchange protein EPAC and via cAMP gated ion channels in the cell membrane.
Positive_regulation (activation) of GTP-exchange protein
1) Confidence 0.02 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650605 Disease Relevance 0.19 Pain Relevance 0.07

General Comments

This test has worked.

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