INT263224

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Context Info
Confidence 0.76
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpv4) plasma membrane (Trpv4) cilium (Trpv4)
transmembrane transport (Trpv4)
Trpv4 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 46 97.36 Very High Very High Very High
Inflammation 7 78.00 Quite High
Pain 4 75.28 Quite High
Hyperalgesia 3 69.76 Quite High
Thermal hyperalgesia 2 64.08 Quite High
Spinal cord 8 56.36 Quite High
TRP channel 13 52.00 Quite High
spinal dorsal horn 19 48.64 Quite Low
Hippocampus 5 37.68 Quite Low
depression 4 35.16 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 46 97.36 Very High Very High Very High
INFLAMMATION 7 78.00 Quite High
Pain 3 75.28 Quite High
Hyperalgesia 5 69.76 Quite High
Nociception 8 55.84 Quite High
Hypersensitivity 2 42.84 Quite Low
Depression 4 35.16 Quite Low
Stress 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A somewhat unexpected observation in this study was the increased ubiquitination of TRPV4 upon ?
Phosphorylation (ubiquitination) of TRPV4
1) Confidence 0.76 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2943294 Disease Relevance 0 Pain Relevance 0
The results suggest that phosphorylation of TRPV4 by PKC is capable of sensitizing this channel.
Phosphorylation (phosphorylation) of TRPV4
2) Confidence 0.70 Published 2009 Journal Mol Pain Section Body Doc Link PMC2650694 Disease Relevance 0.73 Pain Relevance 0.49

General Comments

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