INT263225

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.46
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.75
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpv4) plasma membrane (Trpv4) cilium (Trpv4)
transmembrane transport (Trpv4)
Trpv4 (Mus musculus)
Pain Link Frequency Relevance Heat
Dorsal horn neuron 1 87.84 High High
central sensitization 2 84.24 Quite High
Hippocampus 6 78.60 Quite High
qutenza 17 77.32 Quite High
spinal dorsal horn 19 75.12 Quite High
bradykinin 3 71.88 Quite High
substance P 3 71.28 Quite High
TRP channel 34 71.12 Quite High
calcitonin gene related peptide 3 71.12 Quite High
Neuropeptide 1 70.60 Quite High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 5 97.48 Very High Very High Very High
Stress 1 96.48 Very High Very High Very High
Rhinitis 2 95.20 Very High Very High Very High
Disease 5 82.16 Quite High
Diabetes Mellitus 2 80.00 Quite High
Increased Venous Pressure Under Development 1 73.36 Quite High
Hyperalgesia 6 47.68 Quite Low
Ganglion Cysts 46 44.60 Quite Low
Pain 4 41.04 Quite Low
Loss Of Sense Of Smell 8 30.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activation of TRPV4 may be induced by hypotonic stimuli in response to hypotonicity-induced cell swelling [3-5] and shear stress [6].
Positive_regulation (induced) of Positive_regulation (activation) of TRPV4 associated with stress and pressure and volume under development
1) Confidence 0.46 Published 2010 Journal F1000 Biol Rep Section Body Doc Link PMC2948364 Disease Relevance 0.27 Pain Relevance 0.03
Hypotonicity-induced activation of TRPV4 requires its interaction with the water channel aquaporin (AQP) 5 [9].
Positive_regulation (requires) of Positive_regulation (activation) of TRPV4
2) Confidence 0.46 Published 2010 Journal Acta Oto-Laryngologica Section Body Doc Link PMC2981077 Disease Relevance 0.09 Pain Relevance 0.11
Hypotonicity-induced activation of TRPV4 requires its interaction with the water channel aquaporin (AQP) 5 [9].
Positive_regulation (induced) of Positive_regulation (activation) of TRPV4
3) Confidence 0.46 Published 2010 Journal Acta Oto-Laryngologica Section Body Doc Link PMC2981077 Disease Relevance 0.10 Pain Relevance 0.11
Although PDBu can modulate synaptic transmission by itself, we observed that activation of TRPV4 and PKC, synergistically increased the frequency of mEPSCs as shown with TRPV1 [25].
Positive_regulation (increased) of Positive_regulation (activation) of TRPV4
4) Confidence 0.43 Published 2009 Journal Mol Pain Section Body Doc Link PMC2650694 Disease Relevance 0.29 Pain Relevance 0.44

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox