INT263255

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.88
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (AGTR1) signal transducer activity (AGTR1)
AGTR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
nud 1 71.80 Quite High
Pain 30 57.36 Quite High
pregabalin 1 51.48 Quite High
Gabapentin 1 50.60 Quite High
carbamazepine 1 49.16 Quite Low
Analgesic 5 46.12 Quite Low
cINOD 2 42.20 Quite Low
Neuropathic pain 4 38.52 Quite Low
Acute pain 1 34.92 Quite Low
aspirin 4 12.16 Low Low
Disease Link Frequency Relevance Heat
Proteinuria 21 98.60 Very High Very High Very High
Fabry Disease 192 98.04 Very High Very High Very High
Renal Disease 46 97.04 Very High Very High Very High
Diabetes Mellitus 9 95.24 Very High Very High Very High
Chronic Renal Failure 26 91.28 High High
Hypertension 19 91.20 High High
Vomiting 3 85.48 High High
Vertigo 3 84.88 Quite High
Deafness 9 83.08 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 82.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While speculative, it is intriguing to consider the possibility that more directed pharmacologic therapy might derive from findings like these; for example, blockade of the AT1R with angiotensin receptor blockade might be especially beneficial in these patients [17].
Negative_regulation (blockade) of Negative_regulation (blockade) of angiotensin receptor
1) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2650781 Disease Relevance 1.00 Pain Relevance 0
The use of angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) is useful in patients with proteinuria (Table 3) [299].
Negative_regulation (inhibitors) of Negative_regulation (blockers) of angiotensin receptor associated with proteinuria
2) Confidence 0.03 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC3009617 Disease Relevance 1.89 Pain Relevance 0.25

General Comments

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