INT263281

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Context Info
Confidence 0.41
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CDH1) cell adhesion (CDH1) Golgi apparatus (CDH1)
plasma membrane (CDH1) cytoplasm (CDH1)
CDH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 2 48.56 Quite Low
Inflammation 11 5.00 Very Low Very Low Very Low
rheumatoid arthritis 5 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 10 89.72 High High
Repression 4 84.12 Quite High
Aggression 2 82.12 Quite High
Cancer 155 81.52 Quite High
Malignant Neoplastic Disease 2 76.64 Quite High
Disease 10 73.12 Quite High
Recurrence 6 69.72 Quite High
Colon Cancer 30 66.24 Quite High
Pathologic Processes 2 53.52 Quite High
Breast Cancer 7 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Table 1 shows the percent identity of the human cadherin-11 and E-cadherin transcripts and 3?
Negative_regulation (shows) of Transcription (identity) of E-cadherin
1) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2650783 Disease Relevance 0.16 Pain Relevance 0
Expression of several transcriptional repressors has been shown to down-regulate CDH1 transcription [3].
Negative_regulation (down) of Transcription (transcription) of CDH1
2) Confidence 0.32 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680015 Disease Relevance 0.86 Pain Relevance 0
The main hallmark of this process is the loss of E-cadherin expression mainly caused by repressed transcription of this gene (CDH1) [2].
Negative_regulation (repressed) of Transcription (transcription) of CDH1
3) Confidence 0.32 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680015 Disease Relevance 0.81 Pain Relevance 0

General Comments

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