INT263318

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Akt1, Gsk3b) cytoplasm (Akt1, Gsk3b) cytosol (Akt1, Gsk3b)
nucleus (Akt1, Gsk3b) plasma membrane (Akt1, Gsk3b) kinase activity (Akt1, Gsk3b)
Akt1 (Mus musculus)
Gsk3b (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 3 70.08 Quite High
Arthritis 2 64.64 Quite High
rheumatoid arthritis 5 57.92 Quite High
Pain 1 33.24 Quite Low
Spinal cord 1 32.04 Quite Low
Disease Link Frequency Relevance Heat
Cancer 9 95.88 Very High Very High Very High
Prostate Cancer 7 82.96 Quite High
INFLAMMATION 3 70.08 Quite High
Disease 4 67.12 Quite High
Colitis 1 65.60 Quite High
Arthritis 2 64.64 Quite High
Rheumatoid Arthritis 5 57.92 Quite High
Breast Cancer 5 50.00 Quite Low
Metastasis 5 47.56 Quite Low
Hypercalcemia 1 34.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Once activated Akt acts on many cellular proteins including mTOR, caspase 9, Bad, IKK, and GSK3?.
Akt Regulation (acts) of GSK3
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2650783 Disease Relevance 0.75 Pain Relevance 0.13

General Comments

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