INT263352

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Glyr1) nucleus (Glyr1) DNA binding (Glyr1)
Glyr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pyramidal cell 4 93.36 High High
Hippocampus 22 86.68 High High
antagonist 6 69.88 Quite High
Spinal cord 22 69.24 Quite High
Glutamate receptor 2 68.72 Quite High
spinal dorsal horn 34 40.52 Quite Low
Calcium channel 2 13.20 Low Low
Pain 12 5.00 Very Low Very Low Very Low
Neuronal excitability 8 5.00 Very Low Very Low Very Low
GABAergic 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Premenstrual Syndrome 12 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Nociception 8 5.00 Very Low Very Low Very Low
Epilepsy 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Inflammatory Pain 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Affective Disorder 2 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M), the inactive stereoisomer of E2, mimicked the inhibitory effect of E2 on IGly (Figure 2A6 and 2B1, P > 0.05, Unpaired Student's t-test), suggesting that E2 inhibition on GlyR is independent of classical ERs.


Neg (independent) Positive_regulation (independent) of Neg (inhibition) Gene_expression (inhibition) of GlyR
1) Confidence 0.07 Published 2009 Journal Mol Pain Section Body Doc Link PMC2651124 Disease Relevance 0 Pain Relevance 0.07
In order to magnify the current, we recorded the GlyR-mediated tonic current by adding 20 ?
Positive_regulation (recorded) of Gene_expression (recorded) of GlyR
2) Confidence 0.07 Published 2009 Journal Mol Pain Section Body Doc Link PMC2651124 Disease Relevance 0 Pain Relevance 0.19

General Comments

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