INT263366

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Dlat) oxidoreductase activity (Glyr1) nucleus (Glyr1)
DNA binding (Glyr1) transferase activity, transferring acyl groups (Dlat)
Anatomy Link Frequency
spinal cord 1
Dlat (Rattus norvegicus)
Glyr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 22 99.84 Very High Very High Very High
spinal dorsal horn 34 88.64 High High
Hippocampus 22 33.92 Quite Low
antagonist 6 33.16 Quite Low
Pyramidal cell 4 20.08 Low Low
Pain 12 5.00 Very Low Very Low Very Low
Neuronal excitability 8 5.00 Very Low Very Low Very Low
GABAergic 6 5.00 Very Low Very Low Very Low
IPN 4 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Premenstrual Syndrome 12 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Nociception 8 5.00 Very Low Very Low Very Low
Epilepsy 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Inflammatory Pain 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Affective Disorder 2 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine which GlyR subunits are responsible for the E2-induced inhibition, we investigated the E2 effects on IGly in HEK293 cells expressing various recombinant GlyRs (Figure 4A).
E2 Spec (determine) Regulation (responsible) of GlyR
1) Confidence 0.03 Published 2009 Journal Mol Pain Section Body Doc Link PMC2651124 Disease Relevance 0 Pain Relevance 0
To test whether E2 effects are different in different times in culture, we investigate the effects of E2 on GlyR in spinal cord and HIP neurons from different days in culture.
E2 Spec (investigate) Regulation (effects) of GlyR in spinal cord associated with spinal cord
2) Confidence 0.03 Published 2009 Journal Mol Pain Section Body Doc Link PMC2651124 Disease Relevance 0 Pain Relevance 0.22

General Comments

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