INT263479

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TBK1) plasma membrane (TBK1) cytoplasm (TBK1)
TBK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 56 99.18 Very High Very High Very High
Inflammation 87 91.84 High High
Inflammatory response 57 5.00 Very Low Very Low Very Low
Inflammatory stimuli 35 5.00 Very Low Very Low Very Low
cytokine 13 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 154 91.84 High High
Disease 6 5.00 Very Low Very Low Very Low
Systemic Inflammatory Response Syndrome 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Bacterial Infection 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Critical Illness 1 5.00 Very Low Very Low Very Low
Hepatotoxicity 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Given, therefore, a quantification of the dynamics of corticosteroids and putative modes of action of CS in regulating the activity of NFkB [73], [74] we test the hypothesis that corticosteroids exert their immunosuppressive effect by enhancing the transcriptional synthesis of NF-kB's inhibitor IkBa (mRNA,IkBa).
Positive_regulation (enhancing) of Transcription (synthesis) of NF-kB associated with corticosteroid
1) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2651450 Disease Relevance 0.32 Pain Relevance 0.46

General Comments

This test has worked.

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