INT263492

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Context Info
Confidence 0.19
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 4.76
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand2) nucleus (Hand2) DNA binding (Hand2)
protein complex (Hand2) transcription factor binding (Hand2)
Anatomy Link Frequency
salivary gland 2
Hand2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 75 99.00 Very High Very High Very High
Inflammation 25 87.36 High High
transdermal 7 50.00 Quite Low
imagery 27 5.00 Very Low Very Low Very Low
Central nervous system 21 5.00 Very Low Very Low Very Low
Pain 17 5.00 Very Low Very Low Very Low
positron emission tomography 12 5.00 Very Low Very Low Very Low
Nerve growth factor 10 5.00 Very Low Very Low Very Low
chemokine 9 5.00 Very Low Very Low Very Low
Peripheral nervous system 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Influenza Virus Infection 35 99.90 Very High Very High Very High
Syndrome 26 96.40 Very High Very High Very High
Adhesions 1 96.36 Very High Very High Very High
Wiskott-aldrich Syndrome 4 96.24 Very High Very High Very High
Eosinophilia 6 95.44 Very High Very High Very High
Thrombocytopenia 2 94.76 High High
Anaemia 1 94.04 High High
Eczema 5 92.40 High High
Tick Infestations 2 91.24 High High
Infection 86 90.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Achieving the most effective immune response against influenza may require an optimal balance of Th1 and Th2 responses.
Spec (may) Positive_regulation (require) of Regulation (responses) of Th2 associated with influenza virus infection
1) Confidence 0.19 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2651574 Disease Relevance 0.43 Pain Relevance 0
Basophils can promote Th2 responses by IL-4 production and both basophils and eosinophils express CD86 and could be targets of salivary gland molecules [47,48].
Positive_regulation (promote) of Regulation (responses) of Th2 in salivary gland
2) Confidence 0.12 Published 2010 Journal Parasit Vectors Section Body Doc Link PMC2993695 Disease Relevance 0.19 Pain Relevance 0.04
and IL-1, whereas Th2 responses occur in presence of IL-4 and IL-10.
Positive_regulation (occur) of Regulation (responses) of Th2
3) Confidence 0.07 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 0.47 Pain Relevance 0.13
An increased Th2 response and elevated IgE levels are observed.
Positive_regulation (increased) of Regulation (response) of Th2
4) Confidence 0.05 Published 2010 Journal Clin Mol Allergy Section Body Doc Link PMC2837605 Disease Relevance 3.68 Pain Relevance 0.04

General Comments

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