INT263760

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Rbm39) RNA binding (Rbm39) nucleus (Rbm39)
Igh-Lev (Mus musculus)
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 6 100.00 Very High Very High Very High
long-term potentiation 52 94.68 High High
Hippocampus 24 5.00 Very Low Very Low Very Low
nMDA receptor 18 5.00 Very Low Very Low Very Low
Pyramidal cell 8 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 16 5.00 Very Low Very Low Very Low
Congenital Anomalies 12 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Influenza Virus Infection 2 5.00 Very Low Very Low Very Low
Contagious Ecthyma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because Neto1, SOL-1, and LEV-10 are associated with neurotransmitter receptors of different classes, our work suggests that a critical interaction with a CUB domain-containing protein may be a general characteristic of ligand-gated ion channels throughout nature.
LEV-10 Binding (associated) of receptors associated with neurotransmitter
1) Confidence 0.00 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0 Pain Relevance 0.21
Our discovery that Neto1 in vertebrates is a component of the NMDAR complex, together with the previous identification of SOL-1 [11] and LEV-10 [13] in C. elegans as CUB domain-containing proteins associated with the GLR-1 and ACh receptors, respectively, suggests that the CUB domain may be an evolutionarily conserved molecular signature of a significant subset of the proteins associated with neurotransmitter receptors.
LEV-10 Binding (associated) of receptors associated with neurotransmitter
2) Confidence 0.00 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0 Pain Relevance 0.11

General Comments

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