INT263765

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.26
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Neto1, Grin1) transport (Grin1) enzyme binding (Grin1)
cytoplasm (Grin1)
Neto1 (Mus musculus)
Grin1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 24 86.40 High High
long-term potentiation 52 64.92 Quite High
nMDA receptor 18 5.00 Very Low Very Low Very Low
Pyramidal cell 8 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
Glutamate receptor 4 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 12 67.16 Quite High
Cognitive Disorder 16 61.68 Quite High
Contagious Ecthyma 2 33.52 Quite Low
Convulsion 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Helminth Infection 2 5.00 Very Low Very Low Very Low
Influenza Virus Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Having shown that Neto1 is a component of the NMDAR complex, we asked whether glutamatergic synaptic transmission and plasticity are altered in the absence of Neto1.
Neto1 Regulation (component) of NMDAR
1) Confidence 0.39 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0.13 Pain Relevance 0.11
Altogether, our findings establish that Neto1 is an important regulator of the NMDAR complex required for normal NMDAR-mediated synaptic plasticity and learning.
Neto1 Regulation (regulator) of NMDAR
2) Confidence 0.39 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0.13 Pain Relevance 0.09

General Comments

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