INT263819

Context Info Confidence 0.25 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.63 Pain Relevance 0.32

lipid binding (PTEN) cell proliferation (PTEN) cytosol (PTEN) plasma membrane (PTEN) nucleus (PTEN) enzyme binding (PTEN)

PTEN (Homo sapiens)

Pain Link Frequency Relevance Heat antagonist 2 72.16 licofelone 4 62.44 cINOD 2 58.60 Inflammation 8 51.00 Osteoarthritis 1 50.16 cytokine 4 5.00 COX-2 inhibitor 3 5.00 Inflammatory response 1 5.00 acular 1 5.00 Inflammatory mediators 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 12 99.44 Non-small-cell Lung Cancer 3 97.32 Colon Cancer 1 65.24 INFLAMMATION 11 58.04 Toxicity 6 56.32 Osteoarthritis 1 50.16 Hepatotoxicity 1 38.80 Cancer 18 34.32 Lung Cancer 21 17.52 Malignant Neoplastic Disease 2 11.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

and affects expression of genes such as PTEN, fibronectin, and integrin alpha 5 [62–64].

Regulation (affects) of Gene_expression (expression) of PTEN

1) Confidence 0.25 Published 2008 Journal PPAR Research Section Body Doc Link PMC2652614 Disease Relevance 0.63 Pain Relevance 0.32

General Comments

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