INT263884

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc2a3) transmembrane transporter activity (Slc2a3) plasma membrane (Slc2a3)
transmembrane transport (Slc2a3) cytoplasm (Slc2a3)
Anatomy Link Frequency
astrocytes 1
Slc2a3 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 4 90.84 High High
Hippocampus 10 90.00 High High
Pyramidal cell 2 69.44 Quite High
Inflammatory response 2 68.00 Quite High
positron emission tomography 36 45.12 Quite Low
imagery 87 44.80 Quite Low
Central nervous system 14 29.60 Quite Low
Somatostatin 12 11.76 Low Low
Inflammation 19 5.00 Very Low Very Low Very Low
Kinase C 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 15 99.84 Very High Very High Very High
INFLAMMATION 21 67.60 Quite High
Dementia 15 50.00 Quite Low
Cancer 214 47.12 Quite Low
Colon Cancer 63 16.16 Low Low
Neuroendocrine Cancer 22 10.68 Low Low
Disease 165 5.00 Very Low Very Low Very Low
Thyroid Neoplasm 53 5.00 Very Low Very Low Very Low
Metastasis 50 5.00 Very Low Very Low Very Low
Diabetes Mellitus 50 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In astrocytes, glucose uptake is mediated by the 45 kDa GLUT1 transporters, whereas GLUT3 transporters mediate this process in neurons.
Gene_expression (transporters) of GLUT3 in astrocytes
1) Confidence 0.18 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 0.07 Pain Relevance 0.19
This entire process is thought to occur more readily in malignant cells than in normal cells due to the overexpression of the glucose transporters GLUT 1 and GLUT 3 by malignant cells and due to higher levels of hexokinase within malignant cells.
Gene_expression (overexpression) of GLUT 3 associated with malignant neoplastic disease
2) Confidence 0.04 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.79 Pain Relevance 0

General Comments

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