INT263912

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 9
Disease Relevance 0.66
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (SLN)
Anatomy Link Frequency
nucleus accumbens 1
anterior pillars 1
nerve 1
muscle 1
amygdala 1
SLN (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 4 98.54 Very High Very High Very High
Nucleus accumbens 4 98.26 Very High Very High Very High
amygdala 4 97.82 Very High Very High Very High
cerebral cortex 6 91.96 High High
insula 4 90.80 High High
medulla 44 83.40 Quite High
Transcranial magnetic stimulation 12 69.52 Quite High
anesthesia 73 69.04 Quite High
lidocaine 8 61.24 Quite High
Central nervous system 20 54.60 Quite High
Disease Link Frequency Relevance Heat
Stroke 8 97.04 Very High Very High Very High
Sleep Disorders 9 79.72 Quite High
Laryngismus 6 74.88 Quite High
Unconsciousness 6 73.96 Quite High
Gastroesophageal Reflux Disease 3 72.72 Quite High
Acid Reflux 4 72.52 Quite High
Breast Cancer 56 67.68 Quite High
Nicotine Addiction 4 14.20 Low Low
Pseudorabies 4 6.32 Low Low
Cancer 426 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experimental studies have shown that stimulating the anterior pillars with a cold probe while simultaneously stimulating the iSLN increases the number of pharyngeal swallows elicited in the anesthetized adult cat [115].
Positive_regulation (stimulating) of iSLN in anterior pillars
1) Confidence 0.39 Published 2010 Journal Dysphagia Section Body Doc Link PMC2992653 Disease Relevance 0 Pain Relevance 0
Stimulation of the iSLN induces a reflex in the recurrent laryngeal nerve, activity in interneurons in the NTS, and simultaneous rostral activation of multiple cortical sites, including a cortical descending reflex that can affect the motoneurons in the cranial motor nuclei and interneurons in the NTS swallowing pathway [144].
Positive_regulation (Stimulation) of iSLN in nerve
2) Confidence 0.26 Published 2010 Journal Dysphagia Section Body Doc Link PMC2992653 Disease Relevance 0.17 Pain Relevance 0.25
Chemical stimulation of the amygdala and nucleus accumbens with dopamine and apomorphine facilitates pharyngeal swallowing induced by electrical stimulation of the SLN in an anesthetized cat [43].
Positive_regulation (stimulation) of SLN in nucleus accumbens associated with nucleus accumbens, dopamine and amygdala
3) Confidence 0.26 Published 2010 Journal Dysphagia Section Body Doc Link PMC2992653 Disease Relevance 0 Pain Relevance 0.22
Likewise, Woznick et al [145] reported in 2006 that although 77% of cases had the first positive SLN identified as the first removed SLN, 23% of cases had the first positive SLN identified as the second, third, fourth, fifth, or sixth SLN removed.
Positive_regulation (had) of SLN
4) Confidence 0.15 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0 Pain Relevance 0
In 2007, Povoski et al [144] demonstrated that although 83% of cases had the first positive SLN identified as the hottest SLN, 17% of cases had the first positive SLN identified as the second, third, fourth, or fifth hottest SLN.
Positive_regulation (had) of SLN
5) Confidence 0.15 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.12 Pain Relevance 0
Chemical stimulation of the amygdala and nucleus accumbens with dopamine and apomorphine facilitates pharyngeal swallowing induced by electrical stimulation of the SLN in an anesthetized cat [43].
Positive_regulation (stimulation) of SLN in amygdala associated with nucleus accumbens, dopamine and amygdala
6) Confidence 0.09 Published 2010 Journal Dysphagia Section Body Doc Link PMC2992653 Disease Relevance 0 Pain Relevance 0.22
After electrical stimulation of iSLN, we can expect the swallowing reflex as well as the laryngeal responses.
Positive_regulation (stimulation) of iSLN
7) Confidence 0.02 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2703761 Disease Relevance 0.08 Pain Relevance 0.18
The esophageal muscle of dogs is entirely composed of striated fibers, and therefore is controlled by cranial motoneurons.24 Accordingly, we can expect the existence of esophageal motility during checking the laryngeal EMG when we stimulate the iSLN.
Positive_regulation (stimulate) of iSLN in cranial motoneurons
8) Confidence 0.02 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2703761 Disease Relevance 0.21 Pain Relevance 0.06
After electrical stimulation of one iSLN, the electromyographic potential can be recorded in the ipsilateral or contralateral thyroarytenoid (TA) muscle.
Positive_regulation (stimulation) of iSLN in muscle
9) Confidence 0.02 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2703761 Disease Relevance 0.07 Pain Relevance 0.06

General Comments

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