INT263917

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.56
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Sstr5) extracellular space (SST) extracellular region (SST)
plasma membrane (Sstr5) cytoplasm (Sstr5) signal transducer activity (Sstr5)
SST (Homo sapiens)
Sstr5 (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 16 100.00 Very High Very High Very High
imagery 89 97.80 Very High Very High Very High
metalloproteinase 1 75.24 Quite High
Bioavailability 1 63.76 Quite High
positron emission tomography 36 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 235 98.04 Very High Very High Very High
Neuroendocrine Cancer 22 97.36 Very High Very High Very High
Colon Cancer 64 80.80 Quite High
Pituitary Cancer 39 48.16 Quite Low
Malignant Neoplastic Disease 15 42.48 Quite Low
Thyroid Neoplasm 54 15.28 Low Low
Disease 65 5.00 Very Low Very Low Very Low
Metastasis 50 5.00 Very Low Very Low Very Low
Skin Cancer 39 5.00 Very Low Very Low Very Low
Breast Cancer 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GH secretion is regulated through ligand binding of somatostatin to both sst2 and sst5, whereas SSA binds preferentially sst2 [26].
somatostatin Binding (binding) of sst5 associated with somatostatin
1) Confidence 0.02 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC3017030 Disease Relevance 0.10 Pain Relevance 0.17
This includes the 111In-labeled somatostatin analogue, 111In-diethylenetriaminepentaacetic acid-D-phenylalanine1-octreotide (111In-DTPA-D-Phe1-octreotide or 111In-pentetreotide), as well as various 111In-labeled monoclonal antibodies. 111In-(DTPA)-D-Phe1-octreotide binds to somatostatin receptors, predominantly of somatostatin receptor subtype sst2 and sst5, and have been useful for diagnostic nuclear medicine imaging of neuroendocrine tumors and of non-neuroendocrine tumors which express somatostatin receptors [26,108].
somatostatin Binding (binds) of sst5 associated with neuroendocrine cancer, somatostatin and imagery
2) Confidence 0.01 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.47 Pain Relevance 0.28

General Comments

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