INT263975

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TBK1) nucleoplasm (NR4A3) plasma membrane (TBK1)
nucleus (NR4A3) DNA binding (NR4A3) cytoplasm (TBK1)
NR4A3 (Homo sapiens)
TBK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 5 99.24 Very High Very High Very High
ischemia 2 97.68 Very High Very High Very High
Inflammation 68 97.12 Very High Very High Very High
cytokine 15 96.60 Very High Very High Very High
agonist 12 33.08 Quite Low
adenocard 16 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 99.48 Very High Very High Very High
INFLAMMATION 74 99.24 Very High Very High Very High
Reperfusion Injury 1 98.44 Very High Very High Very High
Cv Unclassified Under Development 2 97.68 Very High Very High Very High
Atherosclerosis 1 84.72 Quite High
Adhesions 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Graft Vs Host Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NR4A3 prevents NF-kB activation, thereby reducing inflammatory responses such as the generation of pro-inflammatory cytokines.
NR4A3 Negative_regulation (prevents) of Positive_regulation (activation) of NF-kB associated with inflammatory response, inflammation and cytokine
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2654409 Disease Relevance 1.20 Pain Relevance 0.57

General Comments

This test has worked.

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