INT263977

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (JAK2) histone binding (JAK2) cytoplasm (JAK2)
cytosol (JAK2) signal transduction (JAK2) extracellular space (PROC)
Anatomy Link Frequency
neutrophils 1
PROC (Homo sapiens)
JAK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 15 98.76 Very High Very High Very High
Inflammation 68 95.40 Very High Very High Very High
Inflammatory response 5 75.60 Quite High
ischemia 2 70.40 Quite High
adenocard 16 53.28 Quite High
agonist 12 5.80 Low Low
chemokine 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 74 95.40 Very High Very High Very High
Atherosclerosis 1 82.12 Quite High
Stress 1 72.20 Quite High
Reperfusion Injury 1 71.16 Quite High
Cv Unclassified Under Development 2 70.40 Quite High
Adhesions 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low
Graft Vs Host Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Suppressor of cytokine signaling 3 is the main isoform of that family of regulatory factors expressed in neutrophils and functions by inhibiting JAK2 kinase activity [54]–[57].
factors Negative_regulation (inhibiting) of JAK2 in neutrophils associated with cytokine
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2654409 Disease Relevance 0.93 Pain Relevance 0.47

General Comments

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