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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.50
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Anatomy Link Frequency
immune system 1
IFNA1 (Homo sapiens)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 37 100.00 Very High Very High Very High
Inflammatory response 1 80.84 Quite High
Multiple sclerosis 2 75.92 Quite High
Inflammation 13 67.36 Quite High
fibrosis 1 65.76 Quite High
Inflammatory mediators 1 36.56 Quite Low
adenocard 11 5.00 Very Low Very Low Very Low
substance P 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 10 91.68 High High
Disease 34 85.88 High High
Alzheimer's Dementia 5 84.28 Quite High
INFLAMMATION 15 80.48 Quite High
Death 1 77.84 Quite High
Dementia 3 76.68 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 7 76.32 Quite High
Multiple Sclerosis 4 75.92 Quite High
Asthma 1 70.32 Quite High
Inflammatory Bowel Disease 1 67.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A critical role in this process is played by a receptor of the innate immune system, TLR4, and by cytokines, especially IFN?
IFN Binding (receptor) of TLR4 in immune system associated with cytokine
1) Confidence 0.01 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2654796 Disease Relevance 1.50 Pain Relevance 0.22

General Comments

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