INT264143

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TCIRG1, BSND) mitochondrion (TCIRG1) protein complex (BSND)
cytoplasm (BSND) transmembrane transport (TCIRG1)
Anatomy Link Frequency
osteoclast 1
TCIRG1 (Homo sapiens)
BSND (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 1 15.60 Low Low
Demyelination 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
unmyelinated 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteopetrosis 72 99.96 Very High Very High Very High
Malignant Neoplastic Disease 4 97.64 Very High Very High Very High
Obesity 1 26.16 Quite Low
Acidosis 1 22.80 Low Low
Disease 7 5.00 Very Low Very Low Very Low
Sclerosis 6 5.00 Very Low Very Low Very Low
Osteopoikilosis 6 5.00 Very Low Very Low Very Low
Convulsion 5 5.00 Very Low Very Low Very Low
Renal Tubular Acidosis 5 5.00 Very Low Very Low Very Low
Osteomyelitis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TCIRG1 mutations are responsible for autosomal recessive osteopetrosis in more than 50% of affected individuals [38,41] underscoring the crucial role of V-ATPase in osteoclast function.
TCIRG1 Regulation (responsible) of autosomal recessive in osteoclast associated with osteopetrosis
1) Confidence 0.02 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2654865 Disease Relevance 0.74 Pain Relevance 0

General Comments

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