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Context Info
Confidence 0.44
First Reported 1985
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.67
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (APRT) small molecule metabolic process (APRT) transferase activity, transferring glycosyl groups (APRT)
nucleolus (APRT) nucleus (APRT) cytoplasm (APRT)
Anatomy Link Frequency
locus coeruleus 1
APRT (Homo sapiens)
Pain Link Frequency Relevance Heat
Locus ceruleus 11 100.00 Very High Very High Very High
Morphine 16 99.74 Very High Very High Very High
epidural 4 99.08 Very High Very High Very High
analgesia 4 98.72 Very High Very High Very High
tolerance 2 85.60 High High
addiction 2 85.04 High High
opiate 2 65.96 Quite High
antagonist 1 65.32 Quite High
Raphe 1 48.00 Quite Low
Disease Link Frequency Relevance Heat
Injury 4 98.40 Very High Very High Very High
Fever 4 95.32 Very High Very High Very High
Urological Neuroanatomy 1 49.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine.
Regulation (regulation) of AMP in locus coeruleus associated with locus ceruleus and morphine
1) Confidence 0.44 Published 1989 Journal J. Neurosci. Section Title Doc Link 2556507 Disease Relevance 0 Pain Relevance 1.22
The findings are also consistent with regulation of interleukin-1 release which is independent of adrenal stimulation, cyclic AMP or beta-endorphin, as epidural analgesia prevents postoperative increase of these hormones.
Regulation (regulation) of AMP associated with epidural and analgesia
2) Confidence 0.26 Published 1985 Journal Acta Chir Scand Section Abstract Doc Link 3872548 Disease Relevance 0.67 Pain Relevance 0.53

General Comments

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