INT264171
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Bronchoalveolar lavage (BAL) showed an increase in total cell count and an elevated CD4/CD8 ratio compatible with sarcoidosis, and absence of neoplastic cells or infectious agents. | |||||||||||||||
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However, it is possible that the CD4+ T cell values at the lesion-visits may in fact represent the “elevated” values due to increased activation of CD4+ and other immune cells in response to HSV-2 reactivation which may exacerbate CD4+ T cell loss. | |||||||||||||||
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Another possible caveat of the method used in this study is that surface CD25 and intracellular Foxp3 expressions are not strictly specific of Treg cells in humans, as both these markers are upregulated after activation in a significant proportion of CD4+ non-regulatory T cells. | |||||||||||||||
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Of direct relevance to inflammation is the demonstration that 5HT enhanced monocyte stimulation of CD4+ T cells and cytokine production following LPS exposure [261]. | |||||||||||||||
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AITD patients were more likely than controls to be severely compromised at baseline and to experience greater CD4 increments following HAART. | |||||||||||||||
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General Comments
This test has worked.