INT264193

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGAX) plasma membrane (ITGAX)
Anatomy Link Frequency
CD86 2
ITGAX (Homo sapiens)
Pain Link Frequency Relevance Heat
corticosteroid 1 66.48 Quite High
cINOD 1 64.72 Quite High
cytokine 16 51.40 Quite High
chemokine 6 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 26 93.60 High High
Hookworm Infection 35 72.56 Quite High
INFLAMMATION 6 64.32 Quite High
Malaria 1 56.72 Quite High
Parasitic Infection 2 54.12 Quite High
Worm Infection 13 45.16 Quite Low
Helminth Infection 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Eosinophilia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While this is indeed the case for matured DCs from non-infected donors, mDCs from Necator-infected individuals have a down-regulated expression of antigen-presenting, costimulatory (CD86) molecules, and CD11c, with the CD14 still present on the cell surface.
Regulation (regulated) of Gene_expression (expression) of CD11c in CD86
1) Confidence 0.17 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2654967 Disease Relevance 0.41 Pain Relevance 0.12

General Comments

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