INT264269

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.47
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Darc) signal transducer activity (Darc)
ANC (Homo sapiens)
Darc (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 63 100.00 Very High Very High Very High
cytokine 9 98.74 Very High Very High Very High
Pain 3 76.88 Quite High
Catecholamine 3 34.52 Quite Low
Disease Link Frequency Relevance Heat
Cancer 27 96.56 Very High Very High Very High
Sickle Cell Anemia 9 93.76 High High
Neutropenia 27 88.16 High High
Disease 9 86.04 High High
Pain 3 76.88 Quite High
Metastasis 3 54.12 Quite High
Breast Cancer 6 49.96 Quite Low
Stress 3 32.56 Quite Low
Malaria 3 5.44 Low Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We analysed the association of DARC rs2814778 genotype with WBC and ANC, as well as other factors thought to be associated with WBC, in an ethnically diverse sample of women without serious illness.
ANC Spec (analysed) Binding (association) of DARC associated with chemokine
1) Confidence 0.09 Published 2008 Journal British Journal of Haematology Section Body Doc Link PMC2655355 Disease Relevance 0.21 Pain Relevance 0.22
In a linear regression model that included percentage African ancestry, national origin, cytokines, socio-economic factors and the ELA2 rs57834246 SNP, only the DARC rs2814778 genotype and C-reactive protein were associated with ANC (P < 0ยท0001).
ANC Binding (associated) of DARC associated with cytokine
2) Confidence 0.09 Published 2008 Journal British Journal of Haematology Section Abstract Doc Link PMC2655355 Disease Relevance 0.38 Pain Relevance 0.09
This study is the first to show an association between the DARC rs2814778 CC genotype, common among individuals of African descent, and low ANC.
ANC Binding (association) of DARC associated with chemokine
3) Confidence 0.08 Published 2008 Journal British Journal of Haematology Section Body Doc Link PMC2655355 Disease Relevance 0.89 Pain Relevance 0.22

General Comments

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