INT264295

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 1.38
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DMD) signal transduction (IGF1) extracellular space (IGF1)
extracellular region (IGF1) cytoskeleton (DMD) nucleus (DMD)
Anatomy Link Frequency
spine 1
DMD (Homo sapiens)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 135 99.84 Very High Very High Very High
Inflammation 90 42.20 Quite Low
Infliximab 20 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
methotrexate 10 5.00 Very Low Very Low Very Low
visual analogue scale 5 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Inflammatory marker 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 135 99.84 Very High Very High Very High
Hypercalcemia 85 73.44 Quite High
Osteoporosis 40 72.00 Quite High
Disease 95 53.76 Quite High
INFLAMMATION 100 42.20 Quite Low
Obesity 35 40.16 Quite Low
Nicotine Addiction 20 39.52 Quite Low
Endometriosis (extended) 55 5.00 Very Low Very Low Very Low
Insulin Resistance 10 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, higher levels of IGF-1 and IGFSD at baseline for all patients and higher levels of IGF-1 and IGFSD at 12 months for the NoP-group were associated with better BMD at both skeletal sites.
BMD Binding (associated) of IGF-1
1) Confidence 0.07 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0 Pain Relevance 0
Also, in the NoP-group a higher IGF-1 at 12 months correlated with better BMD at the femoral neck after two years (r = 0.31, p = 0.009) and a higher IGFSD at 12 months was associated with better BMD at the lumbar spine at two years (r = 0.26, p = 0.029).
BMD Binding (associated) of IGF-1 in spine
2) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0 Pain Relevance 0
There are limited data about IGF-1 and its association with BMD in RA [21].
BMD Binding (association) of IGF-1 associated with rheumatoid arthritis
3) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0.67 Pain Relevance 0.20
Thus, higher levels of IGF-1 and IGFSD at baseline for all patients and higher levels of IGF-1 and IGFSD at 12 months for the NoP-group were associated with better BMD at both skeletal sites.
BMD Binding (associated) of IGF-1
4) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0 Pain Relevance 0
The present study on patients with early RA was performed to investigate: the effects of glucocorticoid treatment on bone remodelling markers in relation to BMD; to find possible predictors of changes in BMD; and to study the association of IGF-1 in relation to bone markers and BMD.


BMD Binding (association) of IGF-1 associated with rheumatoid arthritis
5) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0.72 Pain Relevance 0.24

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox