INT264319

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.67
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Olr614)
Olr614 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Arthritis 136 100.00 Very High Very High Very High
cytokine 26 69.72 Quite High
depression 2 59.68 Quite High
Inflammation 40 50.00 Quite Low
methotrexate 82 43.60 Quite Low
rheumatoid arthritis 34 5.00 Very Low Very Low Very Low
imagery 26 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 140 100.00 Very High Very High Very High
Synovitis 2 95.36 Very High Very High Very High
Experimental Arthritis 8 92.20 High High
Stress 2 86.00 High High
Immunization 12 74.48 Quite High
Body Weight 8 69.16 Quite High
Disease 26 67.76 Quite High
Pressure And Volume Under Development 54 64.96 Quite High
Erythema 2 64.16 Quite High
Depression 2 59.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated whether the protective activity of T-614 was mediated through a decrease in the severity of all of these clinical indices, or whether the activity of T-614 affected only specific pathogenetic processes.
Spec (whether) Positive_regulation (activity) of T-614
1) Confidence 0.03 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.97 Pain Relevance 0.26
Induction of CIA in rats and T-614 treatment
Positive_regulation (Induction) of T-614 associated with arthritis
2) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.70 Pain Relevance 0.19

General Comments

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