INT264328

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Olr614)
Anatomy Link Frequency
inguinal lymph node 2
Olr614 (Rattus norvegicus)
IL-17 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Arthritis 68 94.56 High High
methotrexate 41 86.40 High High
cytokine 13 78.08 Quite High
Inflammation 20 50.00 Quite Low
imagery 13 41.08 Quite Low
rheumatoid arthritis 17 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 70 94.56 High High
Immunization 6 94.20 High High
Pressure And Volume Under Development 27 61.68 Quite High
Disease 13 39.56 Quite Low
INFLAMMATION 19 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 17 5.00 Very Low Very Low Very Low
Autoimmune Disease 4 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Experimental Arthritis 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, T-614 inhibited the elevated IL-17 expression in inguinal lymph node cells in a dose-dependent manner.
T-614 Negative_regulation (inhibited) of Gene_expression (expression) of IL-17 in inguinal lymph node
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656239 Disease Relevance 0.71 Pain Relevance 0.39

General Comments

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