INT264401

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP1) extracellular region (MMP1) proteinaceous extracellular matrix (MMP1)
nucleus (DR1) intracellular (DR1) DNA binding (DR1)
Anatomy Link Frequency
proximal 2
DR1 (Homo sapiens)
MMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 28 50.00 Quite Low
agonist 2 50.00 Quite Low
Arthritis 6 19.44 Low Low
Inflammation 18 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 10 19.44 Low Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Syndrome 12 5.00 Very Low Very Low Very Low
Chondrosarcoma 12 5.00 Very Low Very Low Very Low
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Repression 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
were binding to the DR-1/AP-1 site in the MMP-1 and MMP-13 proximal promoters, this DNA element may also be responsive to treatment with combinations of LG268 and rosiglitazone.
DR-1/AP-1 Binding (binding) of MMP-1 in proximal
1) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0 Pain Relevance 0
were binding to the DR-1/AP-1 site in the MMP-1 and MMP-13 proximal promoters, this DNA element may also be responsive to treatment with combinations of LG268 and rosiglitazone.
DR-1/AP-1 Binding (binding) of MMP-1 in proximal
2) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0 Pain Relevance 0

General Comments

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