INT264419

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.03
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (DR1) intracellular (DR1) DNA binding (DR1)
transcription factor binding (DR1)
DR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 18 96.12 Very High Very High Very High
Arthritis 9 77.24 Quite High
Inflammation 27 67.64 Quite High
metalloproteinase 42 50.00 Quite Low
agonist 3 50.00 Quite Low
rheumatoid arthritis 15 5.00 Very Low Very Low Very Low
Osteoarthritis 15 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 15 77.24 Quite High
Arthropathy 6 76.04 Quite High
INFLAMMATION 30 67.64 Quite High
Chondrosarcoma 18 66.56 Quite High
Disease 6 9.64 Low Low
Syndrome 18 5.00 Very Low Very Low Very Low
Osteoarthritis 15 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 15 5.00 Very Low Very Low Very Low
Repression 9 5.00 Very Low Very Low Very Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
heterodimer to the DR-1 element precludes binding of AP-1 proteins to its site and thereby antagonizes the expression of MMP-1.
Negative_regulation (antagonizes) of DR-1 element Binding (heterodimer) of
1) Confidence 0.08 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0.35 Pain Relevance 0.15
heterodimer to the DR-1 element precludes binding of AP-1 proteins to its site and thereby antagonizes the expression of MMP-1.
Negative_regulation (precludes) of DR-1 element Binding (heterodimer) of
2) Confidence 0.08 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0.34 Pain Relevance 0.15
heterodimer to the DR-1 element precludes binding of AP-1 proteins to its site and thereby antagonizes the expression of MMP-1.
Negative_regulation (precludes) of DR-1 element Binding (binding) of
3) Confidence 0.08 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0.34 Pain Relevance 0.15

General Comments

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