INT264428

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (JUN) nucleoplasm (JUN) nuclear chromosome (JUN)
aging (JUN) nucleus (JUN) DNA binding (JUN)
JUN (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 13 64.96 Quite High
metalloproteinase 28 50.00 Quite Low
agonist 3 50.00 Quite Low
Inflammation 18 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 1 40.40 Quite Low
Bacterial Respiratory Disease 4 28.40 Quite Low
Repression 6 28.16 Quite Low
Chondrosarcoma 12 5.24 Low Low
Urinary Tract Infection 32 5.00 Very Low Very Low Very Low
Pyelonephritis 30 5.00 Very Low Very Low Very Low
Infection 27 5.00 Very Low Very Low Very Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low
Disease 19 5.00 Very Low Very Low Very Low
Sprains And Strains 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest that ceramide-induced TLR4 signaling causes rapid phosphorylation/transcription of proteins involved in IRF3 and AP-1 transcription, including CREB, Fyn, PLC?
Regulation (involved) of Transcription (transcription) of AP-1
1) Confidence 0.10 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2944801 Disease Relevance 0 Pain Relevance 0.03
and AP-1 transcription factors at the DR-1/AP-1 element, and when considering the competitive binding model, one would expect a decrease in PPAR?
Regulation (at) of Transcription (transcription) of AP-1
2) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0 Pain Relevance 0
and AP-1 transcription factors at the DR-1/AP-1 element, and when considering the competitive binding model, one would expect a decrease in PPAR?
Regulation (expect) of Transcription (factors) of AP-1
3) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656243 Disease Relevance 0 Pain Relevance 0

General Comments

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