INT264477

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a, Jun) extracellular space (Il1a) aging (Jun)
extracellular region (Il1a) nucleus (Jun) DNA binding (Jun)
Anatomy Link Frequency
fibroblasts 1
Il1a (Rattus norvegicus)
Jun (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 66 92.08 High High
Inflammation 13 77.44 Quite High
Potency 6 54.64 Quite High
rheumatoid arthritis 18 35.68 Quite Low
Inflammatory stimuli 2 13.56 Low Low
cytokine 11 5.00 Very Low Very Low Very Low
Arthritis 11 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Kaposis Sarcoma 1 97.20 Very High Very High Very High
INFLAMMATION 16 77.44 Quite High
Rheumatoid Arthritis 19 35.68 Quite Low
Arthritis 8 5.00 Very Low Very Low Very Low
Experimental Arthritis 6 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we provide evidence that ERK1/2 contributed to the IL-1-induced activation of AP-1 and NF-IL-6 in synovial fibroblasts.
IL-1 Positive_regulation (activation) of AP-1 in fibroblasts
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656246 Disease Relevance 0.17 Pain Relevance 0.20

General Comments

This test has worked.

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