INT2645

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Context Info
Confidence 0.67
First Reported 1979
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.47
Pain Relevance 1.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ITPA)
Anatomy Link Frequency
blood vessels 1
endothelium 1
optic 1
DLF 1
ITPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 4 99.60 Very High Very High Very High
medulla 5 98.84 Very High Very High Very High
analgesia 2 95.92 Very High Very High Very High
opiate 2 94.12 High High
headache 2 88.84 High High
Demyelination 5 87.48 High High
Sumatriptan 5 86.60 High High
Potency 1 84.68 Quite High
trigeminal ganglion 1 84.52 Quite High
Neuritis 6 82.64 Quite High
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 2 88.84 High High
Demyelinating Disease 6 87.48 High High
Ganglion Cysts 1 84.52 Quite High
Experimental Autoimmune Neuritis 6 82.64 Quite High
Pain 1 75.00 Quite High
Cancer 1 68.88 Quite High
Necrosis 1 68.32 Quite High
INFLAMMATION 3 65.28 Quite High
Neurogenic Inflammation 1 63.52 Quite High
Urological Neuroanatomy 2 29.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The drugs also blocked the accumulation of horseradish peroxidase reaction product within the endothelium and perivascular space on the stimulated side.
Positive_regulation (accumulation) of horseradish in endothelium
1) Confidence 0.67 Published 1992 Journal Brain Res. Section Abstract Doc Link 1324091 Disease Relevance 0.38 Pain Relevance 0.66
To obtain a comprehensive map of brainstem neurons projecting to the spinal cord via the DLF, large injections of horseradish peroxidase (HRP) were made into the lumbosacral spinal cord of cat and rat.
Positive_regulation (injections) of horseradish in DLF associated with medulla and spinal cord
2) Confidence 0.49 Published 1979 Journal J. Comp. Neurol. Section Abstract Doc Link 489790 Disease Relevance 0.07 Pain Relevance 0.58
Intraocular horseradish peroxidase (HRP) accumulated in severed optic axons but was transported with no obvious hindrance in spared axons alongside the lesion.
Positive_regulation (accumulated) of horseradish in optic
3) Confidence 0.49 Published 1990 Journal Exp Brain Res Section Abstract Doc Link 2340874 Disease Relevance 0 Pain Relevance 0
Systemically administered rabbit immunoglobulin (Ig) was demonstrated within the endoneurium of P2 T cell injected nerves by immunofluorescence and the endoneurial blood vessels showed increased permeability to circulating horseradish peroxidase (HRP).
Positive_regulation (increased) of horseradish in blood vessels
4) Confidence 0.49 Published 1995 Journal Brain Section Abstract Doc Link 7655884 Disease Relevance 1.02 Pain Relevance 0.65
In particular, a chloro group para to the hydrazide moiety increased the PGHS-2 selectivity relative to both myeloperoxidase and horseradish peroxidase isozyme C.
Positive_regulation (increased) of horseradish
5) Confidence 0.49 Published 2004 Journal Arch. Biochem. Biophys. Section Abstract Doc Link 15464732 Disease Relevance 0 Pain Relevance 0.04

General Comments

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