INT264555

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (IL15, BCL2) cytoplasm (IL15, BCL2) mitochondrion (BCL2)
aging (IL15) extracellular space (IL15) cell death (BCL2)
Anatomy Link Frequency
T cells 2
IL15 (Homo sapiens)
BCL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 100.00 Very High Very High Very High
rheumatoid arthritis 35 99.76 Very High Very High Very High
Arthritis 9 81.76 Quite High
dexamethasone 12 79.44 Quite High
Inflammation 9 26.84 Quite Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 35 99.76 Very High Very High Very High
Apoptosis 52 97.04 Very High Very High Very High
Seronegative Spondarthritis 5 82.56 Quite High
INFLAMMATION 9 26.84 Quite Low
Adhesions 2 23.32 Low Low
Cancer 2 18.40 Low Low
Necrosis 2 17.92 Low Low
Arthritis 5 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been demonstrated, for example, that monocytes isolated from RA SF express IL-15 [24], a cytokine able to upregulate Bcl-2 expression [3] and to render activated T cells resistant to glucocorticoid-mediated apoptosis [25].
IL-15 Positive_regulation (upregulate) of Gene_expression (expression) of Bcl-2 in T cells associated with rheumatoid arthritis, apoptosis and cytokine
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656252 Disease Relevance 0.92 Pain Relevance 0.35

General Comments

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