INT264574

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MAOA) small molecule metabolic process (MAOA) oxidoreductase activity (MAOA)
MAOA (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 25 99.46 Very High Very High Very High
transdermal 20 95.92 Very High Very High Very High
Dopamine 2 82.12 Quite High
monoamine 5 79.24 Quite High
Serotonin 4 77.16 Quite High
Central nervous system 2 66.96 Quite High
Neurotransmitter 1 60.52 Quite High
depression 22 54.64 Quite High
headache 7 5.00 Very Low Very Low Very Low
tricyclic antidepressant 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 43 54.64 Quite High
Disease 3 44.40 Quite Low
Recurrence 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 7 5.00 Very Low Very Low Very Low
Headache 7 5.00 Very Low Very Low Very Low
Sleep Disorders 3 5.00 Very Low Very Low Very Low
Heart Rate Under Development 3 5.00 Very Low Very Low Very Low
Suicidal Behaviour 3 5.00 Very Low Very Low Very Low
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Weight Gain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experimental studies have demonstrated that the antidepressant-like effect of selegiline requires greater than 70% inhibition of MAO-A activity (Gordon et al 1999).
Positive_regulation (requires) of Negative_regulation (inhibition) of MAO associated with antidepressant
1) Confidence 0.37 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656289 Disease Relevance 0.05 Pain Relevance 0.41

General Comments

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