INT264669

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Context Info
Confidence 0.30
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (AES)
AES (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 88 73.12 Quite High
Parenteral administration 2 66.12 Quite High
imagery 1 63.60 Quite High
depression 4 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Recurrence 20 93.44 High High
Demyelinating Disease 89 73.12 Quite High
Reprotox - General 1 8 61.36 Quite High
Phobia 4 51.24 Quite High
Cognitive Disorder 7 46.64 Quite Low
Hypoactive Sexual Desire Disorder 2 30.88 Quite Low
Lipodystrophy 1 29.68 Quite Low
Gynecomastia 1 28.76 Quite Low
Galactorrhea 1 28.20 Quite Low
Necrosis 1 23.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a study of discontinuation patterns in patients receiving IFN beta, patients who stopped therapy as a result of AEs did so after a median period of 13 months on treatment, whereas those who discontinued as a result of treatment failure (defined as non-reduction in pre-treatment relapse rate and/or sustained increase of Expanded Disability Status Scale score of ?
Positive_regulation (stopped) of Positive_regulation (result) of AEs associated with recurrence
1) Confidence 0.30 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC2819898 Disease Relevance 0.41 Pain Relevance 0.20
This may suggest that the frequency of prolactin-related AEs associated with paliperidone ER therapy is underestimated.


Positive_regulation (underestimated) of Positive_regulation (frequency) of AEs
2) Confidence 0.22 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656329 Disease Relevance 0.18 Pain Relevance 0

General Comments

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