INT264719

Context Info Confidence 0.28 First Reported 2008 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.12 Pain Relevance 0

cell adhesion (Hes1) nucleus (Hes1) intracellular (Hes1) protein complex assembly (Hes1) DNA binding (Hes1) transcription factor binding (Hes1)

Hes1 (Mus musculus)

Pain Link Frequency Relevance Heat imagery 16 5.00 ketamine 2 5.00 anesthesia 2 5.00 Central nervous system 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Cancer 75 73.08 Ganglion Cysts 2 12.72 Adhesions 7 5.00 Medulloblastoma 7 5.00 Disease 6 5.00 Apoptosis 5 5.00 Brain Tumor 3 5.00 Neurodegenerative Disease 3 5.00 Injury 3 5.00 Body Weight 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Decreases in the expression levels of Pax6, Hes1, nestin, and Sox2 suggest that the immature RPCs had begun undergoing differentiation toward more mature states while co-cultured on the polymer scaffolds.

Regulation (Decreases) of Gene_expression (expression) of Hes1

1) Confidence 0.28 Published 2008 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2802414 Disease Relevance 0 Pain Relevance 0

We report here a novel level of regulation of HES1 expression that is driven by miR-199b-5p, which binds to the HES1 3?

Regulation (regulation) of Gene_expression (expression) of HES1

2) Confidence 0.26 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2656623 Disease Relevance 0.12 Pain Relevance 0

General Comments

This test has worked.