INT264723

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Notch1) Golgi apparatus (Notch1) plasma membrane (Notch1)
nucleus (Notch1) embryo development (Notch1) cytoplasm (Notch1)
Anatomy Link Frequency
ventricular zone 2
Notch1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 12 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 75 99.04 Very High Very High Very High
Neurodegenerative Disease 3 88.40 High High
Medulloblastoma 7 80.56 Quite High
Toxicity 1 78.80 Quite High
Recurrence 1 68.16 Quite High
Death 1 67.60 Quite High
Brain Tumor 3 46.60 Quite Low
Malignant Neoplastic Disease 1 46.08 Quite Low
Breast Cancer 1 41.48 Quite Low
Lung Cancer 2 40.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Persistent expression of bHLH HES1, the principal Notch-responsive gene, prevents both migration of neural progenitor cells out of the ventricular zone and expression of neuronal markers [21].
Negative_regulation (prevents) of Gene_expression (expression) of Notch in ventricular zone
1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2656623 Disease Relevance 0.83 Pain Relevance 0

General Comments

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