INT264778

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CA2, Gabbr1) lyase activity (CA2) signal transducer activity (Gabbr1)
response to stress (CA2) cytosol (CA2) extracellular space (CA2)
CA2 (Homo sapiens)
Gabbr1 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 20 100.00 Very High Very High Very High
Potency 10 81.56 Quite High
agonist 45 27.04 Quite Low
antagonist 10 7.92 Low Low
cocaine 7 5.00 Very Low Very Low Very Low
addiction 7 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
GABAergic 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 13 5.00 Very Low Very Low Very Low
Drug Dependence 5 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Spasticity 2 5.00 Very Low Very Low Very Low
Absence Epilepsy 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of interest, this effect of Ca2+ was not observed with baclofen, suggesting that the chlorophenyl group of baclofen prevents the action of Ca2+ ions, pointing to the possibility that Ca2+ directly binds within the GABA binding site in the GABAB1 VFT.
Ca2 Binding (binds) of GABAB1 associated with gaba
1) Confidence 0.02 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2656813 Disease Relevance 0 Pain Relevance 0.21

General Comments

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