INT264804

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GOPC) plasma membrane (GOPC) cytoplasm (GOPC)
CNNM2 (Homo sapiens)
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 55 100.00 Very High Very High Very High
Potency 12 5.00 Very Low Very Low Very Low
antagonist 9 5.00 Very Low Very Low Very Low
Central nervous system 7 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
Thalamus 3 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroleptic Malignant Syndrome 19 100.00 Very High Very High Very High
Disease 4 5.00 Very Low Very Low Very Low
Psychosis 2 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 1 5.00 Very Low Very Low Very Low
Tremor 1 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With respect to the mAChRs, McN-A-343 (4-(m-Chlorophenylcarbamoyloxy)-2-butynyltrimethylammonium chloride; Fig. (7)), probably the first mAChR agonist known to display functional selectivity [87], was actually found to interact allosterically with [3H]NMS in an equilibrium radioligand binding assay on rat atrial M2 mAChRs over twenty years ago [ 4].
M2 Binding (interact) of Fig associated with neuroleptic malignant syndrome and agonist
1) Confidence 0.00 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2656816 Disease Relevance 0.18 Pain Relevance 0.30

General Comments

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