INT264830

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Ppp1ca) nucleus (Ppp1ca) cell cycle (Ppp1ca)
carbohydrate metabolic process (Ppp1ca) cell division (Ppp1ca) cytoplasm (Ppp1ca)
Ppp1ca (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 10 91.84 High High
Dopamine 2 86.12 High High
amygdala 4 85.36 High High
Hippocampus 9 76.32 Quite High
addiction 35 65.32 Quite High
Thalamus 2 36.80 Quite Low
cerebral cortex 2 25.04 Quite Low
Pyramidal cell 1 12.56 Low Low
Glutamate 1 7.12 Low Low
cocaine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 2 55.04 Quite High
Apoptosis 4 45.60 Quite Low
Frailty 2 29.04 Quite Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Drug Dependence 7 5.00 Very Low Very Low Very Low
Cold Sores 7 5.00 Very Low Very Low Very Low
Recurrence 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, in its activated state as pThr34-DARPP-32, it becomes a robust inhibitor of protein phosphatase 1 (PP-1), a substrate responsible for de-phosphorylation of numerous cellular targets.
Regulation (responsible) of Phosphorylation (phosphorylation) of PP-1
1) Confidence 0.05 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2656817 Disease Relevance 0.06 Pain Relevance 0.27

General Comments

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