INT264835

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Tpr) mitochondrion (Creb1) nucleus (Creb1)
molecular_function (Tpr) DNA binding (Creb1) transcription factor binding (Creb1)
Creb1 (Mus musculus)
Tpr (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 35 76.72 Quite High
drug abuse 5 50.40 Quite High
withdrawal 6 30.16 Quite Low
dopamine receptor 1 25.64 Quite Low
Hippocampus 9 13.64 Low Low
Nucleus accumbens 10 12.40 Low Low
cocaine 6 5.00 Very Low Very Low Very Low
Morphine 6 5.00 Very Low Very Low Very Low
amygdala 4 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 7 50.40 Quite High
Pheochromocytoma 1 36.12 Quite Low
Recurrence 4 24.80 Low Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Cold Sores 7 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subsequent to phosphorylation at Ser133, CRE-bound CREB can exert its influence upon target gene transcription and interact with promoter-bound cofactors.
CREB Binding (interact) of promoter
1) Confidence 0.01 Published 2007 Journal Current Neuropharmacology Section Body Doc Link PMC2656817 Disease Relevance 0.05 Pain Relevance 0.06

General Comments

This test has worked.

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