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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) cell-cell signaling (POMC) cytoplasm (POMC)
extracellular space (POMC) generation of precursor metabolites and energy (POMC) signal transduction (POMC)
Anatomy Link Frequency
neutrophils 1
POMC (Homo sapiens)
BOC (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 40 100.00 Very High Very High Very High
Opioid 67 93.72 High High
Inflammation 38 72.60 Quite High
antagonist 15 66.32 Quite High
Pain 28 61.72 Quite High
Delta opioid receptors 2 55.36 Quite High
analgesia 20 51.36 Quite High
ischemia 1 46.08 Quite Low
chemokine 5 15.84 Low Low
IPN 19 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 38 72.60 Quite High
Nociception 24 65.56 Quite High
Pain 29 61.72 Quite High
Pneumococcal Infection 1 54.72 Quite High
Reperfusion Injury 1 46.08 Quite Low
Peritonitis 1 24.96 Low Low
Inflammatory Pain 19 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our studies fMLP- as well as Mycobacterium butyricum-induced Met-enkephalin release could be completely blocked by Boc-FLFLF and partially blocked by cyclosporine H in human neutrophils (Fig. 4C, 6B and Tables 1 and 2).
Met-enkephalin release Binding (blocked) of Boc in neutrophils associated with enkephalin
1) Confidence 0.07 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2657213 Disease Relevance 0.44 Pain Relevance 0.89

General Comments

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