INT264950

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 1.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (FPR1, BOC) endosome (FPR1) signal transduction (FPR1)
cell adhesion (BOC) signal transducer activity (FPR1)
Anatomy Link Frequency
neutrophils 2
FPR1 (Homo sapiens)
BOC (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 80 100.00 Very High Very High Very High
Opioid 134 95.68 Very High Very High Very High
Delta opioid receptors 4 90.04 High High
narcan 16 83.92 Quite High
mu opioid receptor 2 83.52 Quite High
analgesia 40 78.48 Quite High
Inflammation 76 74.56 Quite High
antagonist 30 66.32 Quite High
Pain 56 63.68 Quite High
withdrawal 24 49.84 Quite Low
Disease Link Frequency Relevance Heat
Nociception 48 91.96 High High
INFLAMMATION 76 74.56 Quite High
Pain 58 63.68 Quite High
Pneumococcal Infection 2 54.72 Quite High
Reperfusion Injury 2 46.08 Quite Low
Inflammatory Pain 38 44.64 Quite Low
Peritonitis 2 24.96 Low Low
Hyperalgesia 12 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our studies fMLP- as well as Mycobacterium butyricum-induced Met-enkephalin release could be completely blocked by Boc-FLFLF and partially blocked by cyclosporine H in human neutrophils (Fig. 4C, 6B and Tables 1 and 2).
fMLP Binding (blocked) of Boc in neutrophils associated with enkephalin
1) Confidence 0.11 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2657213 Disease Relevance 0.45 Pain Relevance 0.91
Boc-FLFLF dose-dependently reduced fMLP-FITC binding to human neutrophils (Fig. 4A).
fMLP Binding (binding) of Boc in neutrophils
2) Confidence 0.11 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2657213 Disease Relevance 0.22 Pain Relevance 0.64

General Comments

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