INT264953

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 1.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (POMC, TLR4) signal transduction (POMC, TLR4) small molecule metabolic process (POMC)
intracellular (TLR4) cell-cell signaling (POMC) extracellular space (POMC)
POMC (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 40 100.00 Very High Very High Very High
agonist 15 99.96 Very High Very High Very High
Opioid 67 96.72 Very High Very High Very High
Pain 28 96.00 Very High Very High Very High
antagonist 15 92.00 High High
opioid receptor 8 91.52 High High
imagery 4 90.64 High High
withdrawal 12 87.00 High High
Inflammation 38 81.36 Quite High
IPN 19 79.28 Quite High
Disease Link Frequency Relevance Heat
Pain 29 96.00 Very High Very High Very High
Nociception 24 82.80 Quite High
INFLAMMATION 38 81.36 Quite High
Inflammatory Pain 19 79.28 Quite High
Arthritis 3 64.40 Quite High
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Post Operative Pain 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Met-enkephalin release was triggered by Mycobacterium butyricum and formyl peptides but not by TLR-2 or TLR-4 agonists.
Met-enkephalin release Binding (triggered) of TLR-4 associated with agonist and enkephalin
1) Confidence 0.03 Published 2009 Journal PLoS Pathogens Section Abstract Doc Link PMC2657213 Disease Relevance 0.89 Pain Relevance 1.96

General Comments

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