INT265005

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.15
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sds) lyase activity (Sds) cellular_component (Sds)
cellular amino acid metabolic process (Sds) cytoplasm (Sds)
Anatomy Link Frequency
neurons 1
spermatozoa 1
Sds (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 104 100.00 Very High Very High Very High
Action potential 18 91.32 High High
Peripheral nerve injury 16 90.08 High High
Nicotine 1 80.44 Quite High
adenocard 8 51.20 Quite High
Dorsal horn neuron 13 50.00 Quite Low
Neuronal excitability 7 42.88 Quite Low
cytokine 17 5.00 Very Low Very Low Very Low
Spinal cord 14 5.00 Very Low Very Low Very Low
Glutamate 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Injury 92 96.96 Very High Very High Very High
Disease 1 79.16 Quite High
Necrosis 5 50.00 Quite Low
Cancer 5 50.00 Quite Low
Neuropathic Pain 25 39.60 Quite Low
Stress 4 37.20 Quite Low
Aging 6 15.32 Low Low
Adult Respiratory Distress Syndrome 9 5.00 Very Low Very Low Very Low
Injury 9 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LDH and SDH are widely distributed and located in the seminiferous tubules and germ cells, which is associated with the maturation of spermatogenic cells, testis and spermatozoa and the energy metabolism of spermatozoa.
Localization (located) of SDH in spermatozoa
1) Confidence 0.35 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994374 Disease Relevance 0 Pain Relevance 0
Reagent kits of alkaline phosphatase (AKP), acid phosphatase (ACP), lactate dehydrogenase (LDH), superoxide dismutase (SOD), reduced glutathione hormone (GSH), malondialdehyde (MDA), sorbitol dehydrogenase (SDH), alanine aminotransferase (ALT), aspartate aminotransferase (AST), nitric oxide (NO) and nitric oxide synthase (NOS) were purchased from Nanjing Jiancheng Bioengineering Institute (CHINA).


Localization (aminotransferase) of SDH
2) Confidence 0.35 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994374 Disease Relevance 0 Pain Relevance 0
The percentage of sampled SDH neurons firing in a tonic manner ranged from 45–60% and was not significantly affected by SNI or TNF?
Localization (firing) of SDH in neurons associated with nervous system injury and dorsal horn
3) Confidence 0.28 Published 2009 Journal Mol Pain Section Body Doc Link PMC2657778 Disease Relevance 1.07 Pain Relevance 0.40
The remarkable formation of a stable, globular lipoprotein from constituent S-MB and SDS is attributed to the N-terminal residues (1–7) in S-MB (Fig. 2), as analogous dimers are not observed in SDS-PAGE of MB (Fig. 8).
Localization (attributed) of SDS
4) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0
Succinic acid dehydrogenase (SDH) is an enzyme localized within cells in the Mt matrix and an important step in the Krebs cycle [13, 17].
Localization (localized) of SDH
5) Confidence 0.18 Published 2010 Journal International Journal of Dentistry Section Body Doc Link PMC2990858 Disease Relevance 0.08 Pain Relevance 0.07

General Comments

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